Synthesis of 5-Chloro-7-iodo-8-quinolinol Sulfate
نویسندگان
چکیده
منابع مشابه
A potential anticancer agent: 5-chloro-7-iodo-8-hydroxyquinolinium dichlorido(5-chloro-7-iodoquinolin-8-olato-κ2 N,O)palladium(II) dihydrate
The title Pd(II) coordination compound, (C(9)H(6)ClINO)[PdCl(2)(C(9)H(4)ClINO)]·2H(2)O, was prepared as a potential anti-cancer agent. Its structure is ionic and consists of a square-planar [PdCl(2)(CQ)](-) complex anion (CQ is 5-chloro-7-iodo-quinolin-8-olate), with the Pd(II) atom surrounded by two chloride ligands in a cis configuration and one N,O-bidentate CQ mol-ecule, a protonated anion ...
متن کامل5-Chloro-8-hydroxyquinolinium nitrate
The 5-chloro-8-hydroxy-quinolinium cation in the the title ion pair, C(9)H(7)ClNO(+)·NO(3) (-), is approximately coplanar with the nitrate anion [dihedral angle = 16.1 (1)°]. Two ion pairs are hydrogen bonded (2 × O-H⋯O and 2 × N-H⋯O) about a center of inversion, generating an R(4) (4)(14) ring.
متن کاملAntifungal activity of 5-, 7-, and 5,7-substituted 2-methyl-8-quinolinols.
2-Methyl-8-quinolinol and sixteen 5-, 7-, and 5,7-substituted derivatives with fluoro, chloro, bromo, iodo, nitro, and amino substituents were tested for in vitro antifungal activity against five fungi, Aspergillus niger, A. oryzae, Trichoderma viride, Myrothecium verrucaria, and Trichophyton mentagrophytes. The 5,7-dichloro and 5,7-dibromo derivatives were the most fungitoxic of the compounds ...
متن کاملSpectrophotometric Determination of Tantalum(V) with 5-Iodo-8- -hydroxyquinoline-7-sulphonic Acid
Tantalum(V) reacts with 5-iodo-8-hydroxyquinoline-7-sulphonic acid to form a yellowish coloured complex having maximum absorbance at 405 nm in citric acid medium. The relatively slow reaction at room temperature is completed in 10 minutes at 40 °c. The colour is stable for at least 12 hr. Effects of heating temperature, time, pH, reagent concentration and other variables have been studied. The ...
متن کاملDesign, synthesis and anti-HIV integrase evaluation of N-(5-chloro-8-hydroxy-2-styrylquinolin-7-yl)benzenesulfonamide derivatives.
Styrylquinoline derivatives are demonstrated to be HIV-1 integrase inhibitors. On the basis of our previous CoMFA analysis of a series of styrylquinoline derivatives, N-[(2-substituted-styryl)-5-chloro-8-hydroxyquinolin-7-yl]-benzenesulfonamide derivatives were designed and synthesized,and their possible HIV IN inhibitory activity was evaluated.
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ژورنال
عنوان ژورنال: Chemical and Pharmaceutical Bulletin
سال: 1973
ISSN: 0009-2363,1347-5223
DOI: 10.1248/cpb.21.911